Cold thermogenesis 7 by Dr Jack Kruse

This is copy-pasted article from Dr Jack Kruse. All the credit to drjackkruse. Please follow him to find the truth about sun based life. 

Let’s go over a day in a warm-adapted animal’s circadian cycle (assuming you wake up around 6:00 a.m.).

What happens first thing in the morning?
There’s a surge of cortisol, a hormone involved with fat, protein and carbohydrate metabolism.
VIP is at its highest level.
Ghrelin, a hunger hormone, is at a high level.
Note: Ghrelin has a half-life of one hour.
In healthy individuals, ghrelin is high and drops fast when food is eaten.
In obese individuals, ghrelin is low and remains elevated, even if food is eaten.
Blood pressure is at its highest.
What happens at daybreak?
The sun hits the retina, beginning the shutdown of melatonin (an antioxidant that protects nuclear and mitochondrial DNA) from the pineal gland in the brain.

After an hour of light exposure (7:30 a.m.), melatonin is shut off from the brain.

What happens at 8:30 a.m.?
The gastrocolic reflex (the urge for a bowel movement) is stimulated and cortisol, ghrelin, blood pressure and aldosterone (a hormone tied to blood pressure) are elevated.

Around 9-10 a.m.:
Highest secretions of steroid sex hormones.
This makes us feel very alert.

2:30 p.m.:
Ideal muscle contraction.

3:30 p.m.:
Fastest motor reaction times in our central nervous system.

5 p.m.:
We’re at our greatest level of cardiovascular efficiency, as well as protein synthesis.
This makes this a good time of day to workout.

6:30 p.m.:
Change in blood pressure.

7 p.m.:
Gradual rise in body temperature.
Leptin and interleukin 6 (IL-6) are released from fat stores, signaling the brain about our fat mass and inflammatory status.

The next 2-to-3 hours:
Leptin levels rise.
Insulin levels fall.
Adiponectin, a protein that regulates glucose levels, falls.
Adenosine levels are rising, signaling sleepiness.

10 p.m.:
Melatonin secretion begins after 3-4 hours of total darkness.
Leptin rises quickly to enter the brain.

11:30 p.m.:
GI tract is shut down.
Vagus nerve is quiet.

Midnight-3 a.m.:
Leptin enters the hypothalamus.
If you’re leptin resistant, this doesn’t occur.
Insulin spikes block leptin ability to enter the brain.
If you’re leptin sensitive, the hypothalamus sends a signal to the thyroid, upregulating function and efficiency, raising your basal metabolic rate and burning fat (making heat instead of energy).
There’s a surge of the hormone prolactin.
This is diminished by artificially-lit environments.
Or if you eat 3-4 hours near bedtime.
Autophagy is at its highest efficiency.
Growth hormone is released.


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